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Updated: Jul 17, 2025

Screening for Functional Non-coding Genetic Variants Using Electrophoretic Mobility Shift Assay EMSA and DNA-affinity Precipitation Assay DAPA
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基于基因的负担得分可以确定28种血液生物标志物的罕见变异关联

Rana Aldisi1, Emadeldin Hassanin2,3, Sugirthan Sivalingam2,4,5

  • 1Institute of Genomic Statistic and Bioinformatics, University Hospital Bonn, Bonn, Germany. s0raaldi@uni-bonn.de.

BMC genomic data
|September 4, 2023
PubMed
概括

这项研究整合了常见和罕见的遗传变异,用于风险预测. 虽然罕见变异会影响个体特征,但常见变异多基因风险评分 (PRS) 更好地预测人口层面对复杂疾病的遗传易感性.

关键词:
血液中的生物标志物复杂的表型复杂的表型基因关联 基因关联基因预测的基因预测在PRS中使用PRS.罕见的变种 罕见的变种

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