连续化疗随后进行放射治疗与同步化疗辐射在肌肉侵入性膀癌中
Mohammad Hasan Larizadeh1, Fateme Arabnejad2, Mohammad Reza Ebadzadeh3
1Associate professor of radiation oncology, Neuroscience Research Center, Institute of Neuropharmacology, Kerman University of Medical Sciences, Kerman, Iran
Urology journal
|September 5, 2023
概括
顺序化疗和放射治疗为肌肉侵入性膀癌患者提供相似的整体存活率,与同时治疗相比. 这种方法提供了比较少的三模式治疗更好的结果,尽管复发率更高.
科学领域:
- 在瘤学瘤学.
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
背景情况:
- 膀癌通常在老年人中被诊断出来.
- 标准治疗包括激进囊切除术或三模式治疗 (TURB,并发化疗辐射).
- 由于并发症,许多患者无法接受三种模式治疗.
研究的目的:
- 为了比较顺序与并发化疗和放射治疗在肌肉侵入性膀癌的疗效.
- 评估两种治疗方式之间的生存率和复发率.
主要方法:
- 一项涉及266名患有肌肉侵入性膀癌的患者的研究.
- 连续化疗和放射治疗与并发化疗和放射治疗的比较.
- 评估整体存活率,无病存活率和复发率.
主要成果:
- 在顺序和并发治疗组之间观察到类似的整体存活率.
- 顺序组表现出较低的无病存活率.
- 同时组的复发率更高.
结论:
- 顺序化疗和放射治疗显示,与并发治疗相比,整体存活率相当.
- 这种顺序方法比涉及不到三种模式治疗的治疗方法产生更好的结果.
- 顺序治疗对于那些无法同时接受化学辐射的患者来说是一个可行的选择.
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