在患有 Post-bariatric 低血糖症患者的认知
Alexa Puleio1, Amanda Sheehan1, Gail Musen1,2
1Research Division, Joslin Diabetes Center, Boston, Massachusetts, USA.
Obesity (Silver Spring, Md.)
|September 5, 2023
概括
患有腹后低血糖症 (PBH) 的个体经历了显著的认知缺陷,特别是在口语流和认知灵活性方面,与腹手术后没有PBH的人相比.
科学领域:
- 神经科学是一个神经科学.
- 内分泌学 在内分泌学.
- 心理学 心理学 心理学
背景情况:
- 腹腔外科手术有效治疗肥胖症,但可能导致腹腔后低血糖症 (PBH).
- 在PBH患者中,复发性低血糖症的认知影响在很大程度上是未知的.
- 了解这些影响对于管理手术后患者健康至关重要.
研究的目的:
- 为了研究PBH和没有PBH的个体在减肥手术后认知功能差异.
- 为了确定PBH是否与记忆,执行功能,注意力或精神运动速度受损有关.
主要方法:
- 一项涉及14名经过Roux-en-Y胃绕道术的成年人的比较研究.
- 参与者被分为两个组:PBH+ (n=7) 和PBH- (n=7).
- 认知评估包括对记忆,执行功能,注意力和精神运动速度的测量.
主要成果:
- PBH+个体在类别流性和类别切换任务中的表现显著下降.
- 在PBH+组的初始和第三间隔中观察到言语流性受损.
- 在两组之间的其他认知评估中没有发现显著差异.
结论:
- 患有PBH的人可能面临更高的认知障碍风险.
- 语义处理和认知灵活性受损是PBH患者的主要担忧.
- 发起和维持单词检索的困难表明PBH中存在特定的认知挑战.
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