糖尿病患者的健康饮食模式和心血管疾病风险:一项前性队列研究
Xiaohui Liu1, Yin Li1, Yang Ao1
1Department of Endocrinology, The Second Affiliated Hospital, Department of Nutrition, School of Public Health, Zhejiang University School of Medicine, Hangzhou 310058, Zhejiang, China. jingjingjiao@zju.edu.cn.
Food & function
|September 5, 2023
概括
坚持健康的饮食模式,如替代地中海饮食 (AMED),可显著降低糖尿病患者心血管疾病 (CVD) 的风险. 这项研究支持管理糖尿病中心血管疾病并发症的饮食指南.
科学领域:
- 营养流行病学 营养流行病学
- 预防心血管疾病 预防心血管疾病
- 糖尿病管理 糖尿病管理
背景情况:
- 关于特定的饮食模式如何影响糖尿病患者心血管疾病 (CVD) 风险的证据有限.
- 了解这些关联对于开发有针对性的饮食干预来缓解高风险人群中心血管疾病并发症至关重要.
研究的目的:
- 调查坚持三种不同的饮食模式与大量糖尿病患者中心血管疾病发病率之间的关系.
- 评估一般健康饮食,替代地中海饮食 (AMED) 和饮食方法阻止高血压 (DASH) 饮食对心血管疾病风险的具体影响.
主要方法:
- 一项前性队列研究,涉及22473名来自英国生物银行的糖尿病患者.
- 通过使用食物频率问卷和牛津WebQ24小时饮食回忆来评估饮食摄入量.
- 在多变量调整后,使用Cox比例危险模型来分析饮食模式与心血管疾病发病率之间的关联.
主要成果:
- 在平均10.8年的随访期间,记录了5209例心血管疾病事件,其中包括3552例冠状动脉疾病 (CHD) 和881例中风.
- 坚持更高的健康饮食模式与降低心脏病,心脏病和中风风险有显著的关联.
- 替代地中海饮食 (AMED) 也显示出与心血管疾病发病率的保护性关联,而DASH饮食没有显示出显著的影响.
结论:
- 坚持健康的饮食模式,包括AMED,与糖尿病患者心血管疾病发病率较低有关.
- 这些发现提供了强有力的证据,支持制定旨在减少心血管疾病负担和糖尿病人群中并发症的饮食指南.
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