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Updated: Jul 17, 2025

Proton Transfer and Protein Conformation Dynamics in Photosensitive Proteins by Time-resolved Step-scan Fourier-transform Infrared Spectroscopy
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Proton Transfer and Protein Conformation Dynamics in Photosensitive Proteins by Time-resolved Step-scan Fourier-transform Infrared Spectroscopy

Published on: June 27, 2014

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面对相位问题的解决方法

Wayne A Hendrickson1

  • 1Department of Biochemistry and Molecular Biophysics, Columbia University, New York, NY 10032, USA.

IUCrJ
|September 5, 2023
PubMed
概括

在X射线晶体学中,相位问题已经通过不断发展的方法,如异常衍射和分子替换来克服. 人工智能和冷电子显微镜 (cryo-EM) 的进步现在为确定原子结构提供了强大的替代方案.

关键词:
异常衍射异常的衍射情况密度的修改 密度的修改直接方法 直接方法同型的替代物是同型的替代物.分子替代的分子替代.

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