在运动参与者队列中的关节保护手术后异型骨化低剂量预防方案
Matteo Olivero1, Bruno Capurro2, Pedro Reis-Campos3
1Centro Traumatológico Ortopédico, (CTO), University of Torino, 10126 Torino, Italy.
SICOT-J
|September 5, 2023
概括
与小型开放手术相比,关节镜显著降低了骨塞 (FAI) 手术后异型骨化 (HO) 的风险. 在接受FAI治疗的运动员中,为期两周的埃托利科克西布疗法有效地预防了HO.
科学领域:
- 整形外科手术 整形外科手术
- 运动医学 运动医学
- 药理学 药理学是指药理学的学科.
背景情况:
- 不同类型的骨化 (HO) 是已知的并发症后的手术治疗为股骨支柱入 (FAI).
- 在关节镜手术 (0-44%) 和部开放手术 (18.2-25%) 之间,HO的发病率差异很大.
- 目前的预防通常涉及NSAID或选择性COX-2抑制剂.
研究的目的:
- 调查使用选择性COX-2抑制剂的低剂量预防方案是否能降低接受关节保护手术的运动员的HO风险.
- 为了比较关节镜和前部迷你开放FAI治疗之间的HO发病率.
主要方法:
- 在2008-2018年间对98名运动员进行FAI (关节镜或前部迷你开放) 治疗的前性分析.
- 术后预防,每天服用60毫克埃托里科克西布,持续两周.
- 1,3个月和12个月的HO (布鲁克分类) 放射检查;进行了二变量和回归分析.
主要成果:
- 在迷你开放组 (6名患者) 中,HO发生在13.6%的患者中,而在关节镜组 (54名患者) 中为0%.
- 手术类型是唯一与HO发展显著相关的变量 (p=0.007).
- 与文献数据相比,埃托里科克西布治疗方案在预防HO方面表现出有效性.
结论:
- 与FAI前部小型开放手术相比,关节镜术与HO的风险较低.
- 长达两周的每日60毫克埃托里科克西布治疗方案在FAI手术后的运动员中对HO预防有效.
- 该协议提供了一个可行的选择,以减轻这种患者群体中HO风险.
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