牛奶相关症状评分 (CoMiSS):从布里斯托尔到布鲁塞尔的便尺度
Katerina Bajerova1,2, Silvia Salvatore3, Christophe Dupont4
1From the Department of Pediatrics, University Hospital Brno and Masaryk's University, Brno, Czech Republic.
在牛奶相关症状评分 (CoMISS) 工具中,将布里斯托尔便形式尺度 (BSFS) 替换为布鲁塞尔婴幼儿便尺度 (BITSS) 并不会改变在婴儿中识别牛奶过敏症状的临床实践. 观察到的变化仅在低风险的婴儿身上.
科学领域:
- 儿科 儿科 儿科
- 过敏和免疫学 过敏和免疫学
- 胃肠病学 胃肠病学
背景情况:
- 牛奶相关症状评分 (CoMISS) 是评估婴儿牛奶相关症状的认识工具.
- 布里斯托尔便形状尺度 (BSFS) 是CoMISS中常用于未经所训练的婴儿的标准.
研究的目的:
- 评估将BSFS替换为布鲁塞尔婴儿和幼儿便量表 (BITSS) 是否会影响COMISS总体得分.
- 为了确定这种替代物是否会影响临床决策,对婴儿潜在的牛奶过敏.
主要方法:
- 一项涉及13个月以下未经所训练的婴儿的比较研究.
- 使用BSFS (CoMISS-BSFS) 和BITSS (CoMISS-BITSS) 评估了CoMISS的分数. 这些分数包括:
- 统计分析包括威尔科克森签名等级测试和皮尔森相关性.
主要成果:
- 在整个数据集中,在CoMISS-BSFS和CoMISS-BITSS之间发现了统计学上显著的差异 (P < 0.001).
- 然而,在CoMISS-BSFS得分较高 (≥10,≥12,≥6) 的婴儿中没有观察到显著差异.
- 显著的差异仅限于得分较低的婴儿 (≤5),表明牛奶相关症状的风险较低.
结论:
- 在CoMISS工具中用BITSS取代BSFS不会改变潜在牛奶相关症状的诊断值.
- 便尺度评估的变化不太可能影响CoMISS在诊断牛奶过敏时的临床应用.
- 观察到的得分变化主要局限于被确定为症状风险较低的婴儿.
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