在高近视的儿童和青少年中,轴长度和球体等值的纵向变化
Feng Jiang1, Decai Wang1, Qiuxia Yin1
1State Key Laboratory of Ophthalmology, Zhongshan Ophthalmic Center, Sun Yat-Sen University, Guangdong Provincial Key Laboratory of Ophthalmology and Visual Science, Guangdong Provincial Clinical Research Center for Ocular Diseases, Guangzhou, China.
Investigative ophthalmology & visual science
|September 5, 2023
概括
在儿童中,高近视的进展在11岁以后会减缓,但在病态近视时会加速. 了解这些轴长和球形相当的变化是治疗儿科高近视的关键.
科学领域:
- 眼科医生 眼科 眼科
- 儿科眼科医生 儿科眼科医生
- 近视研究 近视研究
背景情况:
- 高近视是儿童和青少年的重大公共卫生问题.
- 在这个人口群体中,关于轴长度和球形相当的进展的纵向数据对于有效管理至关重要.
- 病态近视症在监测和治疗方面提出了独特的挑战.
研究的目的:
- 在被诊断为高近视的儿童和青少年中跟踪轴长度 (AL) 和球形等值 (SE) 的纵向变化.
- 识别和分析与高近视在这个年龄组的进展相关的风险因素.
主要方法:
- 采用了纵向的观察性队列研究设计.
- 从293名高度近视的参与者 (年龄在7-17岁) 的数据收集了平均7.09年.
- 混合效应回归模型被用来分析AL和SE的变化率,并探索相关的风险因素.
主要成果:
- 对AL的平均变化率为0.13毫米/年,对于SE的平均变化率为0.36毫米/年.
- 在11岁以后,AL和SE的进展显著下降.
- 较高的基线SE和在基线存在的病理近视与加速进展有关.
结论:
- 年龄是一个重要因素,在高近视的儿童和青少年中,在11岁后观察到更慢的进展.
- 病理近视在基线的存在是加速轴长度延长和近视球形等效进展的关键风险因素.
- 这些发现强调了早期检测和监测的重要性,特别是在年幼的儿童和患有病态近视症的儿童中.
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