新诊断结直肠癌患者的并发症模式:基于网络的研究
Hang Qiu1,2, Liya Wang1, Li Zhou3
1Big Data Research Center, University of Electronic Science and Technology of China, Chengdu, China.
JMIR public health and surveillance
|September 5, 2023
概括
结肠直肠癌 (CRC) 患者经常患有多种慢性疾病,其中高血压,前列腺增生和COPD是最常见的. 这些并发症显示出显著的性别和城乡差异,影响了患者的护理.
科学领域:
- 在瘤学瘤学.
- 公共卫生 公共卫生
- 网络医学 网络医学
背景情况:
- 结肠直肠癌 (CRC) 患者经常有多种并发症,影响治疗和生存.
- 之前的研究集中在有限的并发症指数上,忽视了CRC中全方位的慢性疾病.
- 在CRC患者中,综合性并发症模式仍未得到充分研究.
研究的目的:
- 系统地分析新诊断的CRC患者的所有同时出现的慢性诊断.
- 使用基于网络的方法和大规模的行政健康数据绘制共患病模式.
- 提供来自中国西南地区的CRC患者共发病情况的完整图片.
主要方法:
- 使用来自中国四川省678家医院的医院出院记录 (2015-2020年) 的回顾性观察性研究.
- 在2020年确定了新的CRC病例,并使用ICD-10代码分析了他们的病史.
- 为慢性癌症患者和子组 (性别,年龄,区域,癌症部位) 构建了表型并发症网络,重点关注66种患病率>1%的慢性病.
主要成果:
- 总共有29,610个新的CRC病例被分析;75.5%至少有一种并发症.
- 最常见的并发症包括高血压 (29.0%),前列腺增生 (21.9%),和COPD (14.2%).
- 在并发病率和共存方面观察到显著的性别和城乡差异,特定疾病介导相关性.
结论:
- 在并发症模式中观察到的男女和城乡差异并非巧合.
- 结果强调了了解CRC患者个体和并存疾病模式的临床相关性.
- 强调需要在CRC患者管理中进行全面的并发症评估.
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