[移植受体中的COVID-19:墨西哥经验的多中心报告]
Mónica Sánchez-Cárdenas1, Enzo Vásquez-Jiménez2,3, Ricardo I Velázquez-Silva1
1Servicio de Nefrología del Trasplante, Departamento de Nefrología y Metabolismo Mineral, Instituto Nacional de Ciencias Médicas y Nutrición Salvador Zubirán, Ciudad de México, México.
Archivos de cardiologia de Mexico
|September 5, 2023
概括
患有COVID-19的固体器官移植接受者 (SOTR) 经历了严重的并发症,包括住院和急性损伤. 接受脏移植的患者死亡率为12.2%,这突显了这一群体对SARS-CoV-2感染的脆弱性.
科学领域:
- 移植免疫学 移植免疫学
- 传染病 传染病 传染病
- 关键护理医学 关键护理医学
背景情况:
- 固体器官移植接受者 (SOTR) 由于免疫抑制和并发症而面临严重COVID-19的高风险.
- 本研究描述了墨西哥COVID-19的SOTR的临床过程和结果.
- 了解COVID-19对移植患者的影响对于管理至关重要.
研究的目的:
- 评估诊断为COVID-19的和肝移植接受者的临床过程和短期结果.
- 在这个脆弱的患者群体中识别潜在的并发症和死亡率.
主要方法:
- 18岁以上的确诊COVID-19的SOTR (脏和肝脏) 的回顾性评估.
- 从墨西哥的第三级护理中心收集的数据.
- 医院住院,ICU入院,急性损伤和死亡率的分析.
主要成果:
- 45名脏移植接受者:75.5%住院,16.3%在重症监护室,67%患有急性脏损伤,12.2%死亡率.
- 10名肝移植接受者:50%住院,死亡率为0%.
- 接受脏的患者住院时间平均为8天.
结论:
- 移植接受者面临的死亡率增加和SARS-CoV-2感染的并发症.
- 需要进一步的研究来确定SOTR.的预后因素和有效的COVID-19疗法.
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