儿童喘中急性鼻炎的危险因素
Hanrui Wang1,2,3, Jianwei Wang1,2,3, Zheying Song1,2,3,4
1Department of Otorhinolaryngology, Head and Neck Surgery, Yantai Yuhuangding Hospital, Qingdao University, Yantai, China.
International archives of allergy and immunology
|September 5, 2023
概括
较年轻的发病年龄和对Dermatophagoides pteronyssinus (d1) 的过敏敏感性是患有喘儿童急性鼻炎 (ARS) 的关键危险因素. 早期的过敏原干预对于在这个人群中管理ARS至关重要.
科学领域:
- 儿科过敏和免疫学
- 呼吸系统医学 呼吸系统医学
- 临床流行病学 临床流行病学
背景情况:
- 与急性鼻炎 (ARS) 相关的婴儿感染是青少年过敏喘的确立危险因素.
- 然而,对于已经被诊断患有喘的儿童出现ARS的特定风险因素的理解仍然不够充分.
研究的目的:
- 调查和确定与患有喘的儿童急性鼻炎 (ARS) 发病相关的主要危险因素.
主要方法:
- 临床特征的回顾性分析,比较患有ARS的喘儿童 (n=194) 与没有ARS的儿童 (n=799).
- 用单变量和多变量倒向阶段逻辑回归分析来确定风险因素.
主要成果:
- 较年轻的发病年龄和对dermatophagoides pteronyssinus (d1) 的过敏敏感性被确定为喘儿童ARS的独立风险因素.
- 在患有ARS的儿童中观察到血中低乙氨基酸 (EOS) 数量,总IgE水平,以及对皮肤虫物种敏感性降低.
结论:
- 较年轻的发病年龄和对皮肤虫氏素 (d1) 的敏感性是儿童喘中ARS的重要危险因素.
- 应在喘儿童的早期实施积极的过敏原干预策略,以减轻ARS风险.
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