塞尔蒂克范围项目 (爱尔兰儿童综合有效的实验室测试参考间隔) 在罗氏模块化系统的血中进行形状测试的方法和结果
Ann Leonard1,2, Turlough Bolger3, Eleanor Molloy4
1Laboratory Medicine Innovation Hub, Tallaght University Hospital, Dublin, Ireland.
Annals of clinical biochemistry
|September 5, 2023
概括
这项研究为爱尔兰人口的血中形状测试建立了儿科参考间隔. 对,,尿素和肌素的发现与国际研究一致,改善了爱尔兰儿童的代谢健康知识.
科学领域:
- 临床化学 临床化学
- 儿科实验室医学 儿科实验室医学
- 参考间隔研究 参考间隔研究
背景情况:
- 凯尔特人范围项目旨在为爱尔兰儿科人口的常见实验室测试建立参考间隔.
- 这项研究的重点是为血形状测试 (,,尿素,肌) 提供儿科参考间隔.
- 它可以与国际儿科参考间隔研究进行比较.
研究的目的:
- 描述CELTIC范围项目的方法.
- 在爱尔兰人群中呈现血,,尿素和肌的儿科参考间隔.
- 为了促进与国际研究结果的比较,并提高对儿科代谢健康的理解.
主要方法:
- 从一家医院的儿科瘤诊所招募了1023名年龄在17岁以下的儿童.
- 使用罗氏模块化系统进行临床化学分析.
- 根据CLSI指南EP28-A3c进行的统计分析.
主要成果:
- 在1000名受试者中,确立了 (137-143 mmol/L,年龄为0.45-16.99岁) 和 (3.6-4.8 mmol/L,年龄为1-16.99岁) 的血参考间隔.
- 电解质不需要年龄分区,与其他研究一致.
- 呈现了血肌和尿素数据,需要根据年龄和性别进行分区.
结论:
- 儿科形状的发现与国际研究 (如CALIPER,HAPPI,NORDIC) 一致.
- 在CELTIC范围的研究中,使用了1000多名受试者和罗氏模块化分析系统.
- 预计将提高对爱尔兰儿童代谢健康的知识.
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