在359名重症患者中,用CytoSorb进行体外血液净化
Marina Pieri1, Matteo A Bonizzoni1, Alessandro Belletti1
1Department of Anesthesia and Intensive Care, IRCCS San Raffaele Scientific Institute, Milan, Italy.
Blood purification
|September 5, 2023
概括
在重症患者中,用CytoSorb净化血液可降低冲击指标,改善生存结果. 这种血液净化技术在重症监护室 (ICU) 患者中显示出潜在的生存益处.
科学领域:
- 关键护理医学 关键护理医学
- 身体外疗法 身体外疗法
背景情况:
- 危急病患者经常经历炎症失调和器官功能障碍.
- 血液净化是一种潜在的治疗选择,但大规模数据有限.
研究的目的:
- 评估高风险重症监护室 (ICU) 患者的临床结果和存活率,这些患者正在使用CytoSorb进行体外血液净化.
主要方法:
- 分析了一系列连续359名ICU患者接受CytoSorb治疗.
- 患者的诊断包括耐心性心脏骤停,心脏性休克和呼吸衰竭.
- 结果与预测死亡率得分 (SAPS II,SOFA) 进行了比较.
主要成果:
- 观察到的30天死亡率为49%,ICU死亡率为57%,医院死亡率为62%,均低于预测.
- CytoSorb治疗导致冲击参数和血管活性无otropic 评分的减少.
- 没有报告CytoSorb相关的并发症.
结论:
- 在危急病患者中,CytoSorb净化血液有效降低了冲击标记物和血管活性无otropic评分.
- 在这个庞大的患者队列中,治疗表明了潜在的生存益处.
- 用CytoSorb进行体外血液净化是高风险ICU患者的安全和潜在有效干预措施.
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