在视网膜静脉封闭中抗VEGF的治疗中止模式
Amy Basilious1, Julie Duncan2, Bobbi Smuck2
1Department of Ophthalmology, Ivey Eye Institute, St. Joseph's Health Care, London, ON..
Canadian journal of ophthalmology. Journal canadien d'ophtalmologie
|September 5, 2023
概括
对视网膜静脉封闭 (RVO) 的抗血管内皮生长因子 (anti-VEGF) 治疗在大多数患者中断,通常是由于疾病稳定. 分支视网膜静脉封闭 (BRVO) 患者通常比中央视网膜静脉封闭 (CRVO) 患者有更好的结果.
科学领域:
- 眼科医生 眼科 眼科
- 视网膜疾病 视网膜疾病
- 医疗治疗 医疗治疗
背景情况:
- 视网膜静脉封闭 (RVO) 是视力丧失的一个重要原因.
- 抗血管内皮生长因子 (抗VEGF) 治疗是一种常见的RVO治疗方法.
- 了解现实世界的治疗模式对于优化患者护理至关重要.
研究的目的:
- 分析视网膜静脉封闭 (RVO) 患者的真实世界抗VEGF治疗模式.
- 确定治疗中止的原因和影响治疗结果的因素.
主要方法:
- 2015-2021年之前未接受过治疗的RVO患者的回顾性队列研究.
- 收集的数据包括人口统计,诊断,注射频率,治疗持续时间和视力敏度.
- 统计分析比较了分支RVO (BRVO) 和中央RVO (CRVO) 以及停产子组之间的结果.
主要成果:
- 总共分析了219只眼睛,其中2482只注射了抗VEGF注射剂.
- 停药率为76.7%,稳定的疾病是最常见的原因 (45%的所有RVO).
- 与分支RVO (BRVO) 眼相比,中央RVO (CRVO) 眼睛的基线和最终视力敏度较差,尽管这两组都得到了改善.
结论:
- 对RVO的抗VEGF治疗经常被停止,主要是由于疾病的稳定性.
- 分支RVO (BRVO) 患者比中央RVO (CRVO) 患者获得更好的视觉结果.
- 尽管停止了治疗,但抗VEGF疗法对两种RVO亚型都有明显的益处.
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