儿科耳研究协议 (POSt):一项多方法研究,以了解英国儿科耳的负担
Elliot Heward1, James Dempsey2, Judith Lunn3
1Division of Infection, Immunity and Respiratory Medicine, School of Biological Sciences, Faculty of Biology, Medicine and Health, The University of Manchester, Manchester, UK elliotheward@doctors.org.uk.
BMJ open
|September 5, 2023
概括
这项研究调查了英国的儿科耳病 (PO),旨在确定其发生率和对儿童和家庭的影响. 这些发现将为未来对这种常见的儿童耳部感染进行抗生素治疗试验提供信息.
科学领域:
- 儿科 儿科 儿科
- 传染性疾病 传染性疾病
- 流行病学 流行病学
背景情况:
- 儿科耳 (PO) 是儿童中耳感染液体泄漏,经常导致听力损失和发育问题.
- 目前对PO的流行病学数据主要来自低收入国家.
- 了解PO在英国的发病率和影响对于有效的管理和研究至关重要.
研究的目的:
- 为了确定英国儿科耳鼻 (PO) 的发病率.
- 探索PO对儿童和青少年 (CYP) 和他们的家庭日常生活的影响.
- 为一项针对PO的最佳抗生素治疗进行随机对照试验奠定基础.
主要方法:
- 使用临床实践研究数据链 (CPRD) 数据 (2005-2021) 来确定PO发生率和抗菌素处方模式.
- 与CYP和家长/护理人员进行30次半结构面试,以评估PO对日常生活的影响和治疗成功的定义.
- 举办三个专业医疗专注小组,以了解当前的管理,成功指标和试验随机化可接受性,采用专题分析.
主要成果:
- 该研究目前正在进行中,正在进行数据收集和分析.
- 预期的结果将量化英国初级保健机构中PO发生率.
- 定性数据将揭示CYP和受PO影响的家庭的生活经验.
结论:
- 这项研究将提供有关儿科耳鼻发病率和影响的重要英国特异性数据.
- 结果将为临床实践提供信息,并指导未来干预研究的设计.
- 传播包括会议,出版物,社交媒体和面向公众的网页.
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