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相关概念视频

Trial and Error and Algorithm01:12

Trial and Error and Algorithm

143
A problem-solving strategy is a plan of action used to find a solution. Different strategies have distinct action plans. Trial and error involves trying different solutions until one works. For instance, to fix a broken printer, you might check ink levels, ensure the paper tray isn't jammed, and verify the printer's connection to your laptop. This method can be time-consuming but is commonly used. Thomas Edison, for example, used trial and error to find a suitable filament for the light...
143
Heuristics01:21

Heuristics

111
Heuristics are problem-solving strategies that use mental shortcuts to simplify decision-making. Unlike algorithms, which must be followed precisely to achieve a correct result, heuristics offer a general problem-solving framework. They save time and energy but can sometimes lead to less rational decisions.
People often rely on heuristics when faced with an overload of information, limited time, low importance of the decision, limited information, or when a heuristic readily comes to mind. For...
111
Response Surface Methodology01:16

Response Surface Methodology

176
Response Surface Methodology (RSM) is a collection of statistical and mathematical techniques used to develop, improve, and optimize processes. It is particularly valuable when many input variables or factors potentially influence a response variable.
The process of RSM involves several key steps:
176
Structure-Activity Relationships and Drug Design01:28

Structure-Activity Relationships and Drug Design

767
Drug design is a dynamic field that involves discovering and developing new medications based on specific biological targets. This process heavily relies on structure-activity relationships (SAR) and quantitative structure-activity relationships (QSAR) to guide the design and optimization of efficient drugs.
SAR studies the intricate relationship between a drug's chemical structure and biological activity. It focuses on understanding how modifications to a drug's structure can influence...
767
Development of Analytical Methods01:21

Development of Analytical Methods

462
An analytical methodology can be divided into four sequential steps: technique, method, procedure, and protocol. A technique is a scientific principle that rationalizes a specific phenomenon through chemical measurements. Adapting a technique for analyzing a sample of interest is termed a method. The procedure outlines the directions for performing the analysis via an analytical method. The protocol is the detailed guidelines on the procedure, which should be strictly followed to obtain the...
462
Drug Discovery: Overview01:26

Drug Discovery: Overview

8.0K
Drug discovery is a multifaceted process involving extensive screening, testing, and optimization of lead compounds to identify potential new drugs for therapeutic use. It combines several approaches, including screening large numbers of natural products, chemical modification of known active molecules, identification of new drug targets, and rational design based on biological mechanisms and drug-receptor structure. These approaches are carried out in both academic research laboratories and...
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相关实验视频

Updated: Jul 17, 2025

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases
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Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases

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使用自动化技术进行映射练习,以制定搜索策略,以确定系统审查工具.

Anthea Sutton1, Hannah O'Keefe2, Eugenie Evelynne Johnson2,3

  • 1Sheffield Centre for Health and Related Research, School of Medicine and Population Health, The University of Sheffield, Sheffield, UK.

Research synthesis methods
|September 5, 2023
PubMed
概括

开发自动搜索策略有效地识别了系统审查的新工具,减少了手动搜索的负担. 这种方法显著增加了系统审查工具箱中目录的工具数量.

关键词:
自动化自动化自动化自动化证据综合 证据综合信息检索 信息检索在文献搜索中搜索文献.搜索策略 战略 搜索策略系统性审查是系统的审查.

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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System

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Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images SDM-PSI
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相关实验视频

Last Updated: Jul 17, 2025

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05:02

Comparing Bibliometric Analysis Using PubMed, Scopus, and Web of Science Databases

Published on: October 24, 2019

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Drug Repurposing Hypothesis Generation Using the "RE:fine Drugs" System
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Meta-analysis of Voxel-Based Neuroimaging Studies using Seed-based d Mapping with Permutation of Subject Images SDM-PSI
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科学领域:

  • 信息科学 信息科学 信息科学
  • 健康科学 卫生科学 卫生科学
  • 证据综合 证据综合

背景情况:

  • 识别用于系统审查工具的出版物具有挑战性,导致高选负担.
  • "系统审查工具箱"旨在列出系统审查和证据综合的工具.

研究的目的:

  • 开发一个自动搜索策略,用于识别系统审查工具箱的合格记录.
  • 为了减少与手动识别系统审查工具相关的时间和负担.

主要方法:

  • 一个映射练习确定了系统审查工具箱中的论文的PubMed ID.
  • 文本挖掘软件 (耶鲁MeSH分析器,VOS查看器) 识别了常见的MeSH和文本单词.
  • 布尔运算符将术语组合成Ovid MEDLINE的搜索策略.

主要成果:

  • 在策略之前,包括81个软件和55个"其他"工具.
  • 自实施以来,工具箱中增加了146个新工具.
  • 在建立搜索策略和自动警报后,观察到工具添加量的增加.

结论:

  • 从绘图实践中开发的搜索策略有效地识别了系统审查的新工具.
  • 这种方法减少了审查员的负担,并增强了系统审查工具箱.
  • 进一步的研究可以优化记录优先级,并适应非医疗保健学科的策略.