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Updated: Jul 17, 2025

Skeletal Phenotype Analysis of a Conditional Stat3 Deletion Mouse Model
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Published on: July 3, 2020

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Tmem161a通过P38 MAPK通路调节骨形成和骨强度

Takuya Nagai1, Tomohisa Sekimoto1, Syuji Kurogi1

  • 1Division of Orthopaedic Surgery, Department of Medicine of Sensory and Motor Organs, Faculty of Medicine, University of Miyazaki, 5200 Kihara, Kiyotake, Miyazaki, 889-1692, Japan.

Scientific reports
|September 5, 2023
PubMed
概括

在小鼠中,跨膜161a (Tmem161a) 枯竭显著提高了骨密度,厚度和强度. 这通过调节P38 MAPK信号发生,从而增加骨细胞对氧化应激的抵抗力.

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