益生菌可以预防牙腐烂吗?
1City Health Care Partnership CIC, Hull, UK. sara.butt8@nhs.net.
Evidence-based dentistry
|September 5, 2023
概括
益生菌,特别是Lactobacillus rhamnosus,可以预防学龄前儿童的牙. 这一系统性审查发现益生菌可以减少虫病的发生率和唾液中的突变性 estreptococcus,但不能减少牙斑.
科学领域:
- 儿科牙科 儿科牙科
- 微生物学 微生物学
- 预防医学 预防医学
背景情况:
- 牙损是学龄前儿童的重大公共卫生问题.
- 早期干预策略对于预防脏病的发展至关重要.
研究的目的:
- 系统地审查和分析益生菌在预防学龄前儿童牙的有效性.
- 为了确定具有最大效率的特定益生菌菌株.
主要方法:
- 随机对照试验 (RCT) 的系统审查和元分析,遵循PRISMA指南.
- 从创立到2022年4月,在11个数据库中进行文献搜索.
- 数据提取和质量评估由两位独立审稿人进行,并使用RevMan5.4和Stata16.4进行元分析.
主要成果:
- 包括17个涉及3781名学龄前儿童的RCT.
- 益生菌对牙腐烂发生率有预防作用.
- 乳杆菌rhamnosus显著降低了虫病的发生率和唾液中Streptococcus Mutans的数量.
结论:
- 益生菌有效预防学龄前儿童的牙损伤.
- 乳酸菌 (Lactobacillus rhamnosus) 是一个有前途的益生菌菌株,用于预防.
- 可能需要进一步的研究来确认对斑块Streptococcus Mutans的影响.
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