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Updated: Aug 10, 2026

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微质SIRT1激活通过mTORC1抑制减轻视网膜内状层的突触损失

Ke Yao1, Qianxue Mou1, Xiaotong Lou1

  • 1Department of Ophthalmology, Tongji Hospital, Tongji Medical College, Huazhong University of Science and Technology, Wuhan, 430030, China.

Journal of neuroinflammation
|September 5, 2023
PubMed
概括

Sirtuin 1 (SIRT1) 激活通过抑制微质激活和突触损失来保护视神经受伤. 这种神经保护策略可以保护视网膜质细胞,并为视力丧失提供潜在的治疗方法.

关键词:
脱乙化 脱乙化微质细胞中的微质细胞一个SIRT1系统.发生突触损失.在 mTORC1 的情况下,mTORC1 是

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