在县的DUID人口中使用米特拉基宁
1Toxicology Department, Orange County Crime Laboratory, 320 N. Flower St., Santa Ana, CA 92703, USA.
Journal of analytical toxicology
|September 6, 2023
概括
在奥兰治县,在0.24%的药物影响下驾驶 (DUID) 病例中检测到米特拉基宁. 它经常与乙醇和二类药物等其他物质一起发现,表明复杂的损伤情景.
科学领域:
- 法医毒理学 法医毒理学
- 药物损害驾驶的研究研究
背景情况:
- 中关键类化合物米特拉基宁 (Mitragynine) 越来越多地被识别为在药物影响下驾驶 (DUID) 的病例.
- 了解mitragynine在DUID事件中的患病率和与其他物质的同时发生对于公共安全至关重要.
研究的目的:
- 在加利福尼亚州奥兰治县三年时间内分析DUID病例中米特拉金因的发生和特征.
- 调查在米特拉基宁阳性DUID病例中7 - 基米特拉基宁和其他药物的联合检测.
主要方法:
- 从2017-2019年对25398起DUID病例进行了回顾性分析.
- 对米特拉基宁 (>10 ng/mL) 和7-氧米特拉基宁的毒理查.
- 审查警察报告和毒品识别专家评估.
主要成果:
- 在60个 (0.24%) DUID病例中检测到米特拉基宁.
- 度在10.5-960 ng/mL (平均109 ng/mL) 之间.
- 单独从未检测到mitragynine;常见的共发生物质包括乙醇,二,甲基胺,可卡因,芬太尼和海洛因.
结论:
- 米特拉金因在DUID病例中是一个相关的物质,通常是多种药物使用的一部分.
- 需要进一步的研究来阐明米特拉基宁对驾驶障碍的具体贡献.
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