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在 keloids 中比较 intralesional triamcinolone 和verapamil-triamcinolone 注射: 一个单盲随机临床试验

Zahra Haghani-Dogahe¹, Ramin Hadadi², Mojdeh Esmailzadeh¹

¹Burn and Regenerative Medicine Research Center, Guilan University of Medical Sciences, Rasht, Iran.

International wound journal

|September 6, 2023

概括

结合维拉帕米尔和三诺龙注射,为手术性 keloids 提供了优越的治疗方法,与单独使用三诺龙相比,导致更快的症状解决和改善痕外观.

科学领域:

皮肤病学皮肤病学
临床研究临床研究

背景情况:

状体很常见,通常是手术切口造成的变形痕.
目前用于 keloids 的治疗方法具有可变的疗效.

研究的目的:

为了比较单独注射triamcinolone的疗效和与维拉帕米尔联合注射的疗效,用于治疗外科手术 keloids.

主要方法:

一项临床试验将患者分为两组:单独使用triamcinolone (T组) 和使用triamcinolone-verapamil混合物 (VT组).
治疗继续进行,直到胆固醇几乎平坦,或最多进行八次治疗.

主要成果:

两组都出现了改善,但VT组的红斑更快地消失,需要治疗的次数更少.
虽然温哥华痕量表 (VSS) 的得分相似,但VT组取得了更大的改善和更快的痕灵活性.
乙组VT在痕红色,会话数和灵活性方面表现出优异的结果.

结论:

维拉帕米尔和三诺龙的组合在 keloid 治疗中比单独的三诺龙更有效.
维拉帕米尔在增强 keloids 的痕减少疗法方面显示出显著的潜力.

关键词:

一个注射的注射.这是一个内部破裂.凯洛伊德 (keloids) 是一种有机物.这种药物是Triamcinolone.维拉帕米尔 (verapamil) 是一种非常有效的药物.伤口的伤口是伤口.伤口愈合伤口愈合

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