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Updated: Jul 17, 2025

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基于3D的生成性PROTAC链接器设计与强化学习

Baiqing Li1, Ting Ran1, Hongming Chen1

  • 1Guangzhou Laboratory, Guangzhou 510005, Guangdong Province, China.

Briefings in bioinformatics
|September 6, 2023
PubMed
概括

针对蛋白质溶解的嵌合体 (PROTACs) 提供有针对性的蛋白质降解. 一个新的3D生成模型,PROTAC-INVENT,设计了PROTAC连接器,用于改进药物发现.

关键词:
PROTAC链接器设计设计生成型模型的生成型模型.强化学习是一种强化学习.

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