针对特殊风险群体儿童接种疫苗的单一中心经验:一个多学科机构共识协议
Hatice Ezgi Barış1, Eda Kepenekli2, Fikriye İrem Akbolat Sakar3
1Division of Pediatrics, Department of Social Pediatrics, Marmara University Faculty of Medicine, İstanbul, Turkey; Institute of Health Sciences, Marmara University, İstanbul, Turkey.
Turkish archives of pediatrics
|September 6, 2023
概括
这项研究分析了特殊风险群体的儿童疫苗接种数据,发现大多数儿童在癌症后接受了疫苗接种治疗. 制定针对免疫受损儿童的国家指导方针.
科学领域:
- 儿科免疫学 儿科免疫学
- 疫苗学 疫苗学 疫苗学
- 临床儿科 临床儿科
背景情况:
- 儿童疫苗接种能力有所改善,但在特殊风险群体 (SRG) 接种疫苗方面仍然存在知识差距.
- 了解SRG的疫苗接种实践对于定制的免疫策略和改善公共卫生结果至关重要.
- 这项研究解决了需要特定的临床证据来指导SRG内的儿童免疫的需求.
研究的目的:
- 在一个中心分析特殊风险组 (SRG) 中接种疫苗的儿童的临床数据.
- 为SRG儿童免疫策略的具体规划提供临床证据.
- 提出在SRG中为儿童接种疫苗的机构共识和协议.
主要方法:
- 一个单一中心的儿科疫苗接种诊所 (2018-2021) 的患者病历的回顾性研究.
- 从审查的患者记录中提取临床和实验室数据.
- 通过多学科医疗保健专业会议,制定机构疫苗接种协议.
主要成果:
- 181名儿童接受了疫苗接种,其中大多数儿童接受了针对恶性瘤的治疗后的疫苗 (固体瘤,急性淋巴细胞白血病,急性髓性白血病).
- 该研究排除了298名为食物或疫苗过敏接种疫苗的儿童,重点关注其他SRG类别.
- 为癌症幸存者,造血干细胞接受者和实体器官移植接受者制定了机构疫苗接种方案.
结论:
- 迫切需要国家指导方针来规范免疫力低下儿童的疫苗接种实践.
- 从多学科单位共享疫苗接种数据和实践可以为国家政策的制定提供信息.
- 加强知识共享对于改善特殊风险儿科群体的疫苗接种策略至关重要.
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