一些椎间盘的五个原因是无痛的
Dong Ah Shin1, Min Cheol Chang2
1Department of Neurosurgery, Yonsei University College of Medicine, Seoul, Republic of Korea.
Journal of pain research
|September 6, 2023
概括
无痛椎间盘 (HIVDs) 可能发生由于已解决的炎症,机械因素,遗传变化,神经回路重组,或个人疼痛耐受性. 了解这些机制可以改善临床疼痛管理策略.
科学领域:
- 神经外科 神经外科
- 疼痛管理 疼痛管理
- 脊柱疾病 脊柱疾病
背景情况:
- 椎间盘 (HIVD) 是腰部和腿部疼痛的常见原因.
- 然而,HIVD患者的一小部分患者没有经历疼痛,这一现象需要解释.
研究的目的:
- 探索潜在的背后机制无痛的椎间盘的潜在机制.
- 加强对HIVDs的临床理解和疼痛管理方法.
主要方法:
- 文献综述和现有关于疼痛感知和脊柱疾病研究的综合.
- 对无痛HIVDs的案例研究和建议的病因因素的分析.
主要成果:
- 确定了五种无痛HIVD的潜在原因:炎症不足/已解决,没有炎症的机械因素,背部根的基因表达改变,脊柱背部角神经回路重组,以及有效的疼痛应对策略/高疼痛耐受性.
- 这些因素表明,在疼痛感知中,生物,神经和心理因素之间存在复杂的相互作用.
结论:
- 无痛的HIVD可能是各种因素造成的,包括炎症,机械,遗传,神经和心理影响.
- 对这些机制的进一步研究可以完善治疗脊柱疼痛的诊断和治疗策略.
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