多发性硬化症患者的自我管理干预措施:系统审查和元分析协议
Reza Heidari-Soureshjani1, Alireza Nikbakht Nasrabadi1, Masoumeh Zakerimoghadam1
1School of Nursing and Midwifery Tehran University of Medical Sciences Tehran Iran.
Health science reports
|September 6, 2023
概括
本研究系统地审查了多发性硬化症 (MS) 的自我管理干预措施 (SMI),以确定它们在改善患者结果方面的有效性. 结果将指导针对性MS自我管理计划的开发.
科学领域:
- 神经学 神经学
- 康复医学 康复医学 康复医学
- 医疗保健服务研究 医疗服务研究
背景情况:
- 自主管理干预 (SMI) 对于管理多发性硬化症 (MS) 症状,预防复发和提高生活质量至关重要.
- 人们对MS自我管理计划的整体有效性以及哪些具体干预措施能产生最好的结果的理解有限.
- 这项研究解决了关于结构化SMI在改善MS患者 (PwMS) 健康结果方面的知识差距.
研究的目的:
- 系统地评估结构化自我管理干预措施在改善多发性硬化症患者的健康结果方面的有效性.
- 为了比较不同类型的自我管理干预措施对MS患者关键健康结果的有效性.
- 确定自我管理干预措施中最有效的组成部分,以便在特定的多发性硬化症子群体中有针对性地应用.
主要方法:
- 将采用一个系统审查协议,搜索主要数据库 (PubMed,科学网,Scopus,EMBASE,CENTRAL) 和灰色文献.
- 与自我管理和MS相关的关键词将用于2000年至2023年7月发表的文章.
- 使用Cochrane工具进行数据提取和偏差风险评估将由两名独立研究人员进行,并使用STATA中的随机效应模型进行潜在的元分析.
主要成果:
- 目前尚不清楚MS的各种自我管理干预措施 (SMI) 的比较有效性.
- 审查将分析包括生活质量 (QoL),抑郁症,自我效能,疼痛和疲劳在内的结果指标.
- 确定中小企业最有前途的组成部分将是关键的结果.
结论:
- 这些发现将阐明多发性硬化症不同自我管理策略的比较有效性.
- 这项研究将为MS患者设计更有效,更有针对性的自我管理干预措施提供信息.
- 优化的干预措施可以改善症状管理,降低复发率,提高MS患者的生活质量.
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