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三甘油-葡萄糖指数与代谢相关的脂肪肝疾病中的维生素D状态有关
Zhiping Liu1, Wensha Zhang1, Zhiwei Zhao1
1Department of Gastroenterology, Hankou Hospital of Wuhan, Wuhan, Hubei, People's Republic of China.
甘油三糖 (TyG) 指数与代谢相关脂肪肝 (MAFLD) 患者的维生素D缺乏有关. 较高的TyG指数可能表明这种人群中维生素D缺乏的可能性更大.
科学领域:
- 内分泌学 在内分泌学.
- 肝病学 肝病学是一种肝病学.
- 营养科学 营养科学
背景情况:
- 维生素D缺乏与胰岛素耐药性和与代谢相关的脂肪肝疾病 (MAFLD) 有关.
- 甘油三糖指数 (TyG) 作为胰岛素耐药性的可靠指标.
研究的目的:
- 研究诊断为MAFLD的患者的TyG指数和维生素D状态之间的关系.
- 确定TyG指数是否可以作为MAFLD患者维生素D缺乏症的生物标志物.
主要方法:
- 这是一项涉及566名MAFLD患者的回顾性横截面研究.
- 维生素D缺乏和不缺乏组之间的临床特征的比较.
- 斯皮尔曼相关性,逻辑回归和ROC曲线分析以评估关联和诊断疗效.
主要成果:
- 与非维生素D缺乏组相比,维生素D缺乏组的TyG指数水平较高.
- 血清25-基维生素D [25(OH) D]与TyG指数呈负相关性.
- 泰格指数被确定为维生素D缺乏的独立风险因素,其识别AUC为0.744.
结论:
- 在MAFLD患者的TyG指数和维生素D状态之间存在显著的负相关性.
- 提升的TyG指数可能表明MAFLD患者中维生素D缺乏的患病率增加.
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