在沙特阿拉伯的幸存者和非幸存者COVID-19患者之间血液学参数的比较
Naif K Binsaleh1,2, Reem Eltayeb1, Subuhi Sherwani2,3
1Department of Medical Laboratory Science, College of Applied Medical Sciences, University of Ha'il, Hail, Saudi Arabia.
International journal of general medicine
|September 6, 2023
概括
血液学参数,如淋巴细胞和白细胞 (WBC) 计数,以及前血时间 (PT) 和部分血质蛋白时间 (PTT),可以预测COVID-19患者的结果. 较低的计数和改变的PT/PTT表明死亡风险较高.
科学领域:
- 血液学 血液学 血液学
- 传染性疾病 传染性疾病
- 临界护理医学 临界护理医学
背景情况:
- 冠状病毒疾病2019 (COVID-19),由SARS-CoV-2引起,在疫情初期呈现出高死亡率.
- 了解影响COVID-19结果的因素对于患者管理至关重要.
研究的目的:
- 为了调查COVID-19幸存者的血液学概况与非幸存者的血液学概况.
- 为了确定与COVID-19死亡率相关的血液学指标.
主要方法:
- 一项对108名住院COVID-19患者的回顾性研究.
- 患者被分为幸存者 (n=54) 和非幸存者 (n=54) 组.
- 组间血液学参数和临床数据的比较.
主要成果:
- 不幸存者在重症监护室停留时间较长,红细胞 (RBC) 中位数显著降低.
- 所有患者都表现出淋巴细胞减小;较低的淋巴细胞计数与幸存者的更长时间住院/ICU相关.
- 减少白细胞 (WBCs),基,以及改变的前列血时间 (PT) 和部分血栓形成时间 (PTT) 与死亡率有关.
结论:
- 血液学参数是评估COVID-19严重程度和预测患者预后的有价值指标.
- 淋巴细胞,白细胞和基细胞计数,以及PT和PTT,可以预测严重疾病的进展和死亡风险.
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