在经期和绝经后妇女的睡眠障碍期间的夜间心率变化
Irina Virtanen1,2, Päivi Polo-Kantola2,3, Nea Kalleinen2,4
1Department of Clinical Neurophysiology, TYKS-SAPA, Hospital District of Southwest Finland, Turku, Finland.
Behavioral sleep medicine
|September 6, 2023
概括
更年期期间的睡眠障碍对心率变化 (HRV) 的影响很小. 更年期激素治疗 (MHT) 在经历高潮的女性中没有显著改变自主神经功能.
科学领域:
- 生殖内分泌学 生殖内分泌学
- 心血管生理学心血管生理学
- 睡眠医学 睡眠医学
背景情况:
- 在高潮期 (更年期过渡) 期间,睡眠障碍很普遍.
- 睡眠不足与同情活动增加有关,这是心血管风险因素.
- 自主神经系统 (ANS) 功能对心血管健康至关重要.
研究的目的:
- 研究睡眠障碍对高潮妇女自主神经功能的影响.
- 评估更年期激素治疗 (MHT) 对睡眠障碍相关的ANS变化的影响.
主要方法:
- 进行了一项睡眠研究协议,涉及适应,参考和睡眠障碍夜晚.
- 参与者包括17名绝经前妇女和18名绝经后妇女.
- 在MHT或安慰剂治疗六个月前和之后,对夜间心率变化 (HRV) 的测量进行了分析.
主要成果:
- 基线:睡眠障碍增加了绝经后妇女的阴道HRV;绝经前妇女没有变化.
- 六个月 (安慰剂):睡眠障碍增加了绝经前妇女的总HRV和绝经后妇女的非线性阴道HRV.
- 更年期激素治疗 (MHT) 在更年期组中都没有显著影响HRV.
结论:
- 外部睡眠障碍在绝经期间对心率变化 (HRV) 产生了很小的影响.
- 更年期激素治疗 (MHT) 在本研究人群中没有对HRV产生可检测的影响.
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