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Updated: Jul 17, 2025

A Restriction Enzyme Based Cloning Method to Assess the In vitro Replication Capacity of HIV-1 Subtype C Gag-MJ4 Chimeric Viruses
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HIV-1逆转录酶的稳定性与Gag裂变效率相关:逆转录酶相互作用对调节蛋白酶激活的含义

Shih-Han Hsieh1,2, Fu-Hsien Yu1,2, Kuo-Jung Huang1

  • 1Division of Clinical Research, Department of Medical Research, Taipei Veterans General Hospital , Taipei, Taiwan.

Journal of virology
|September 6, 2023
PubMed
概括

艾滋病毒-1蛋白酶激活依赖于Gag-Pol二分化,该二分化由逆转录酶 (RT) 相互作用调节. 向RT/RT相互作用可以通过抑制RT和蛋白酶活性来提供一种新的抗HIV疗法.

关键词:
艾滋病病毒 艾滋病病毒 艾滋病病毒它们是逆转录病毒.反向转录酶的使用

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