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在体内方法评估防晒对高能量的可见光的保护

J Le Digabel¹, J Filiol¹, C Lauze¹

¹R&D, Pierre Fabre Dermo-Cosmétique et Personal Care, Toulouse, France.

Journal of the European Academy of Dermatology and Venereology : JEADV

|September 6, 2023

概括

这项研究引入了一种使用多光谱成像来评估防晒产品对紫外线和高能可见光 (HEV) 的保护的新方法. 研究结果显示,宽频过器在HEV频段提供了优越的保护.

科学领域:

皮肤病学皮肤病学
摄影生物学摄影生物学
生物物理学的生物物理.

背景情况:

阳光的紫外线 (UV) 辐射会通过DNA损伤和氧化应激引起皮肤损伤,包括癌症和光衰老.
防晒主要通过过紫外线来保护,紫外线是用太阳保护因子 (SPF) 测量的.
新兴证据表明,高能可见光 (HEV) 也有助于生物皮肤损伤.

研究的目的:

开发和验证一种新的体内方法,用于评估防晒在广泛光谱的有效性,包括UV和HEV频段.
通过使用多光谱图像分析来评估防晒保护.
提供超越传统的SPF指标的光保护的全面评估.

主要方法:

测试了六种商业防晒 (五种SPF50+有机过器,一种含二二三 [TriAsorBTM]) 和对照剂.
志愿者前臂的多光谱图像在防晒应用前后被捕获,使用从紫外线到红外线的LED.
光反射率图被生成以计算紫外线和可见光吸收水平.

主要成果:

与其他产品相比,带有宽谱过器 (TriAsorBTM) 的防晒在HEV频段 (380-450 nm) 的吸收率显著更高.
所有测试的防晒在365nm (UVA) 的吸收率都相似.
多光谱成像有效地绘制了不同波长的光吸收率.

结论:

多光谱成像提供了一种简单,可靠的体内方法来评估现实世界的防晒保护.
这项技术评估了对所有光照引起的皮肤损伤的保护,包括来自HEV辐射的皮肤损伤.
该研究强调了在防晒有效性评估中考虑HEV光的重要性.

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