在使用双酸盐的患者中,根据假肢类型评估椎骨变化:一项回顾性研究
Begüm Ünlü Kurşun1, Ender Akan2
1Izmir Tinaztepe University, Department of Prosthetic Dentistry, Izmir, Turkey.
Brazilian oral research
|September 6, 2023
概括
这项研究比较了使用双酸盐的患者和使用不同假牙的健康个体的骨密度变化. 部分固定假肢可能更好地保护双酸盐使用者的骨结构,可能降低骨硬化风险.
科学领域:
- 在口腔外科手术中.
- 牙假体 牙假体 牙假体 牙假体
- 放射学 放射学是一门学科.
背景情况:
- 双酸盐通常用于骨质疏松症和其他骨疾病.
- 双酸盐使用者的牙科植入体手术和假牙需要仔细考虑,因为可能存在与药物相关的下巴骨硬化 (MRONJ).
- 脊椎骨结构的变化可以表明骨的健康状况和对治疗的反应.
研究的目的:
- 为了比较使用双酸盐的患者与健康对照者的椎骨中的碎形维度 (FD) 值.
- 评估不同类型的假牙 (完全可拆卸的假牙,可拆卸的部分假牙,部分固定假牙) 如何影响这些骨变化.
- 为了确定双酸盐使用者的最佳假肢选择,以减轻风险.
主要方法:
- 对200名患者 (100名双酸盐使用者,100名对照者) 的全景放射图进行了回顾性分析.
- 使用ImageJ软件和盒子计数方法进行图像分析,以计算摩尔区域的碎形维度 (FD).
- 假肢处理前后FD值的比较.
主要成果:
- 在椎骨变化,患者组和假肢类型 (p < 0.05) 之间发现了显著的相互作用.
- 完全可拆卸或可拆卸部分假牙的患者在对照组中,与双酸盐使用者相比,FD的减少更大.
- 与对照组不同的是,带有部分固定假肢的双酸盐使用者随着时间的推移显示出FD的增加.
结论:
- 对于双酸盐使用者来说,建议使用部分固定假肢,而不是可拆卸的假肢,以帮助预防骨髓缩.
- 了解假肢类型对骨结构的影响对于管理双酸盐患者至关重要.
- 进一步的研究可能会探索长期的结果和特定的假肢设计.
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