Jove
Visualize
联系我们
JoVE
x logofacebook logolinkedin logoyoutube logo
关于 JoVE
概览领导团队博客JoVE 帮助中心
作者
出版流程编辑委员会范围与政策同行评审常见问题投稿
图书馆员
用户评价订阅访问资源图书馆顾问委员会常见问题
研究
JoVE JournalMethods CollectionsJoVE Encyclopedia of Experiments存档
教育
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab Manual教师资源中心教师网站
使用条款与条件
隐私政策
政策

相关概念视频

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs01:25

Antiasthma Drugs: Mast Cell Stabilizers and Anti-IgE Drugs

342
Asthma is a chronic respiratory condition for which new therapeutic avenues, including anti-inflammatory drugs like mast cell stabilizers and anti-IgE treatments, continue to be developed.
Mast cell stabilizers, such as cromolyn (also known as sodium cromoglycate) and nedocromil (Tilade), are effective drugs in asthma management. These stabilizers hinder histamine release by skillfully obstructing the activation of mast cells and other cellular entities. Notably, they navigate this task without...
342
Gene Therapy00:59

Gene Therapy

25.5K
Gene therapy is a technique where a gene is inserted into a person’s cells to prevent or treat a serious disease. The added gene may be a healthy version of the gene that is mutated in the patient, or it could be a different gene that inactivates or compensates for the patient’s disease-causing gene. For example, in patients with severe combined immunodeficiency (SCID) due to a mutation in the gene for the enzyme adenosine deaminase, a functioning version of the gene can be...
25.5K
Antibody Structure01:10

Antibody Structure

60.3K
Overview
Antibodies, also known as immunoglobulins (Ig), are essential players of the adaptive immune system. These antigen-binding proteins are produced by B cells and make up 20 percent of the total blood plasma by weight. In mammals, antibodies fall into five different classes, which each elicits a different biological response upon antigen binding.
The Y-Shaped Structure of Antibodies Consists of Four Polypeptide Chains
Antibodies consist of four polypeptide chains: two identical heavy...
60.3K
Drugs Used in Lower Respiratory Disorders: Overview01:17

Drugs Used in Lower Respiratory Disorders: Overview

487
Lower respiratory tract disorders present challenges that often require skilled and nuanced approaches for effective management. Common ailments, such as asthma and chronic obstructive pulmonary disease (COPD), have prompted the development of intricate treatment strategies involving bronchodilators and anti-inflammatory drugs, each tailored to ease breathing and revitalize the lungs.
Bronchodilators, the first step of respiration enhancement, come in various forms, each with its own mechanism...
487
Tumor Immunotherapy01:27

Tumor Immunotherapy

555
Immunotherapy is a treatment that boosts or manipulates the immune system to fight diseases, including cancer. For instance, by stimulating an immune response through vaccinations against viruses that cause cancers, like hepatitis B virus and human papillomavirus, these diseases can be prevented. Nonetheless, some cancer cells can avoid the immune system due to their rapid mutation and division. The immune response to many cancers involves three phases: elimination, equilibrium, and escape.
555
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

442
Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
442

您也可能阅读

相关文章

通过共同作者、期刊和引用图与本文相关的文章。

排序
Same author

Impact of population-specific pharmacogenomic variants on drug dosing in ICU patients.

The pharmacogenomics journal·2026
Same author

Genes required for <i>Mycobacterium tuberculosis</i> to survive the transition from aerosol to pulmonary alveolar lining fluid and early infection in a model of transmission.

bioRxiv : the preprint server for biology·2025
Same author

Twenty-Year Survival Analysis of Adeno-Associated Virus Vector Serotype 2-Mediated Gene Therapy to the Central Nervous System for CLN2 Disease.

Human gene therapy·2025
Same author

Vectorized Human Antibody-Mediated Anti-Eosinophil Gene Therapy.

Human gene therapy·2024
Same author

Suppression of CNS APOE4 Expression by miRNAs Delivered by the S2 AAVrh.10 Capsid-Modified AAV Vector.

Human gene therapy·2024
Same author

Positron Emission Tomography Quantitative Assessment of Off-Target Whole-Body Biodistribution of I-124-Labeled Adeno-Associated Virus Capsids Administered to Cerebral Spinal Fluid.

Human gene therapy·2023

相关实验视频

Updated: Jul 17, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
03:23

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

Published on: May 10, 2024

804

基因疗法用于免疫球蛋白E,补充介导和eosinophilic疾病.

Odelya E Pagovich1, Ronald G Crystal1

  • 1Department of Genetic Medicine, Weill Cornell Medical College, New York, New York, USA.

Human gene therapy
|September 6, 2023
PubMed
概括

基因疗法和反意义技术通过调节关键免疫组件,为治疗人类疾病提供了新的方法. 这些先进的技术针对免疫球蛋白E,补充剂和埃索因菲尔,以获得治疗效益.

科学领域:

  • 免疫学和遗传学
  • 治疗技术 治疗技术

背景情况:

  • 免疫球蛋白E (IgE),补充剂和埃索诺菲尔对宿主防御至关重要.
  • 这些免疫成分的功能障碍可以导致各种人类疾病.

研究的目的:

  • 审查基因疗法和反意义技术在管理免疫相关疾病中的应用.
  • 探索调节IgE,补充剂和异osinophil水平的方法.

主要方法:

  • 基因疗法和反意义技术应用的文献综述.
  • 对专注于免疫成分调节的研究进行分析.

主要成果:

  • 基因疗法和反感应方法在调节IgE,补充剂和氨基细胞水平方面表现有前途.
  • 这些技术为相关的人类疾病提供了潜在的治疗途径.

结论:

  • 基因疗法和反意义技术代表了治疗免疫功能障碍的创新策略.
  • 向IgE,补充剂和埃索诺菲尔为新疗法开发提供了一条途径.
关键词:
过敏是一种过敏.补充补充补充补充补充补充补充.埃奥西诺菲尔是什么意思基因治疗的基因疗法

更多相关视频

Generation of Recombinant Human IgG Monoclonal Antibodies from Immortalized Sorted B Cells
10:32

Generation of Recombinant Human IgG Monoclonal Antibodies from Immortalized Sorted B Cells

Published on: June 5, 2015

18.5K
Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE
07:10

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE

Published on: April 21, 2019

16.4K

相关实验视频

Last Updated: Jul 17, 2025

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis
03:23

Author Spotlight: Investigating the Pathophysiology of Eosinophilic Esophagitis

Published on: May 10, 2024

804
Generation of Recombinant Human IgG Monoclonal Antibodies from Immortalized Sorted B Cells
10:32

Generation of Recombinant Human IgG Monoclonal Antibodies from Immortalized Sorted B Cells

Published on: June 5, 2015

18.5K
Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE
07:10

Application of Biochip Microfluidic Technology to Detect Serum Allergen-specific Immunoglobulin E sIgE

Published on: April 21, 2019

16.4K