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艾滋病毒-1 Vpr诱导ciTRAN,以防止对前病毒的转录抑制

Vipin Bhardwaj1, Aman Singh1, Aditi Choudhary1

  • 1Molecular Virology Laboratory, Department of Biological Sciences, Indian Institute of Science Education and Research (IISER), Bhopal, India.

Science advances
|September 6, 2023
PubMed
概括

人类免疫缺陷病毒1型 (HIV-1) 劫持了一个称为ciTRAN的圆形RNA,以促进其复制. 这种病毒策略涉及排除通常抑制转录的蛋白质,提供新的治疗点.

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