一个诊断的挑战:毒素菌伪装成桃体新生菌
Amir Hamud1,2, Alexander Brodsky1,2, Riad Khnifes1,2
1Department of Otolaryngology, Head and Neck Surgery, Bnai-Zion Medical Center, Haifa, Israel.
The Laryngoscope
|September 6, 2023
概括
毒素菌可以模仿喉癌,在免疫能力强的个体中出现口腔大病变和部胀. 早期诊断需要考虑这种寄生虫感染,即使没有典型的危险因素.
科学领域:
- 传染性疾病 传染性疾病
- 耳鼻喉科 耳鼻喉科 耳鼻喉科
- 病理学 病理学 病理学
背景情况:
- 毒素,一种寄生虫感染,在免疫能力强的个体中通常会出现轻微的,类似流感的症状.
- 口病变和宫淋巴腺病变是多克索普拉斯莫斯病的不常见表现.
- 桃体瘤的差异性诊断在非典型的传染病呈现时可能具有挑战性.
研究的目的:
- 报告一个不寻常的托克索普拉斯莫斯病例,呈现为性口腔喉病变和宫淋巴腺病变.
- 强调在桃体瘤的差异诊断中考虑毒素的重要性.
- 突出诊断挑战和所需的实验室调查.
主要方法:
- 一个28岁的免疫能力强的女性病例介绍,患有持续的喉痛,单侧部疼痛和耳痛.
- 诊断左下总桃体切除术,以评估疑似桃体瘤.
- 对Toxoplasma gondii感染进行血清检测,包括IgM抗体和IgG激发性测试.
主要成果:
- 对桃体切除样本的组织病理学检查显示了急性和慢性炎症,不包括恶性瘤.
- 实验室调查证实了最近的一次主要感染Toxoplasma gondii.
- 高IgM抗体和低IgG激发率表明急性感染.
结论:
- 毒素症可以不典型地呈现于口腔的性病变和宫淋巴腺病,模仿恶性瘤.
- 免疫能力较强的个体可能会经历毒素菌的严重表现.
- 在这种情况下,高度的怀疑指数和适当的实验室检测对于诊断毒素菌至关重要.
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