主要的逆皮质淋巴结解剖对于转移到逆皮质的半膜瘤的转移
Richard S Matulewicz1,2, Nicole Benfante1, Samuel A Funt3,4
1Department of Surgery, Urology Service, Memorial Sloan Kettering Cancer Center, New York, New York.
The Journal of urology
|September 6, 2023
概括
主要逆腺淋巴结解剖是一种安全有效的治疗纯种子瘤与低体积逆腺转移,使患者能够避免化疗或辐射风险.
科学领域:
- 泌尿器科 泌尿器科 泌尿器科 泌尿器科
- 手术瘤学手术瘤学
- 医学瘤学 医学瘤学
背景情况:
- 结节阳性纯种子瘤的传统治疗包括化疗或放射治疗,具有长期风险.
- 主要逆皮淋巴结解剖 (RPLND) 提供了分期和治疗的替代方案.
研究的目的:
- 评估纯种子瘤患者中初级RPLND的病理和瘤结局.
- 根据辅助药物管理策略来评估无复发生存率.
主要方法:
- 追溯,单一机构的案例系列超过10年.
- 包括45名患有转移到尾骨的纯丸半瘤的患者.
- 主要结局:2年无复发存活率分层通过监测与辅助化疗对比.
主要成果:
- 96%的患者在切除的淋巴结中具有可行的纯种子瘤.
- 对于在监测下管理的患者 (n=29),两年无复发生存率为81% (4次复发).
- 没有观察到逆或内脏复发,也没有死亡. 一名接受辅助治疗的患者 (共16名) 复发.
结论:
- 主要RPLND是安全和有效的纯种子瘤与低体积的形转移.
- 这种方法使大多数患者能够避免与化疗或放射治疗相关的长期毒性.
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