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在出院后,早产期的身体组成和神经发育结果的趋势

Laura E Lach¹, Katherine E Chetta¹, Mathew J Gregoski²

¹Division of Neonatology, Department of Pediatrics, Medical University of South Carolina, Charleston, South Carolina, USA.

|September 6, 2023

概括

在早产婴儿中,更高的无脂肪质量 (FFM) 与更好的神经发育结果有关. 出院时的母乳也对这些婴儿的认知和语言成绩产生了积极的影响.

科学领域:

新生儿科学新生儿科学
儿童营养学儿童营养学
发育儿科发育儿科

背景情况:

早产婴儿的身体组成,特别是无脂肪质量 (FFM),对于神经发育结果至关重要.
关于早产婴儿出院后身体组成变化的数据有限.
空气位移囊造影 (ADP) 是一种评估身体成分的方法.

研究的目的:

调查早产婴儿身体组成 (FFM) 和神经发育结果之间的关联.
在住院和门诊阶段检查身体成分.
探索母乳养在出院时对神经发育的影响.

主要方法:

接受新生儿重症监护室治疗的510名早产婴儿的身体构成用ADP测量.
379名婴儿进行了人体测量,ADP扫描 (FFM,脂肪质量,脂肪百分比z-scores) 和神经发育测试 (CAT/CLAMS,Peabody Gross Motor) 在4-6个月的校正年龄.
多变量分析比较了身体组成测量与新生儿因素和神经发育结果.

主要成果:

婴儿的平均妊娠年龄为32±4.8周,出生体重为1697±932克.
在FFM z-score (住院和门诊ADP) 和认知,语言和总运动得分 (p <0.05) 之间发现了积极的相关性.
出院时的母乳与更高的认知 (β = 0.22) 和语言分数 (β = 0.26) 有关.

结论:

在早产婴儿中增加FFM与改善的认知,语言和毛细运动功能有关.
出院时母乳养显示出与认知和语言发展的积极关联.
身体组成评估和营养支持对于优化早产婴儿神经发育至关重要.

关键词:

气流位移复合体图 (plethysmography) 是一种空气位移复合体图.身体组成身体组成新生儿重症监护病房新生儿重症监护病房神经发育结果的神经发育结果早产的婴儿是早产的婴儿.

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