长期结果的PreserFlo MicroShunt与XEN45凝支架在开放角度的玻璃眼
Matthias Nobl1, Sigrid Freissinger2, Katrin Rudolph1
1Department of Ophthalmology, University Hospital of Munich, Munich, Germany.
概括
无论是MicroShunt还是XEN植入物,都有效降低眼内压力,并降低了开角绿眼病患者的绿眼病药物需求,在两年内显示出良好的安全性.
科学领域:
- 眼科医生 眼科 眼科
- 手术创新 在外科创新.
- 视光眼管理 视光眼管理
背景情况:
- 开角光眼 (OAG) 是不可逆转失明的主要原因.
- 使用青光眼排水装置进行副结膜过,为IOP减轻提供了手术选择.
- 比较像MicroShunt和XEN这样的新型设备对于优化治疗策略至关重要.
研究的目的:
- 在OAG患者中,比较MicroShunt与XEN玻璃眼疏通装置的有效性和安全性.
- 为了评估眼内压力 (IOP) 降低和植入后的药物使用.
- 评估并发症的发生率,并为两种设备定义成功标准.
主要方法:
- 一个回顾性,单中心研究,涉及95名OAG患者的106只眼睛.
- 患者接受了MicroShunt (51只眼睛) 或XEN (55只眼睛) 植入.
- 结果在两年内进行了评估,根据IOP范围定义失败,需要修订或视力丧失. 根据药物使用,成功被归类为完全或合格.
主要成果:
- 在OAG患者中,MicroShunt和XEN都从基线显著降低了OAG患者的平均IOP (p < 0.0001).
- 在手术后的两组中,平均药物使用量显著下降 (p < 0.0001).
- 与XEN相比,MicroShunt的完成率 (37%) 和合格率 (57%) 的成功率相对较高 (分别为25%和45%),尽管人口统计学年龄差异较大.
结论:
- 在OAG中,MicroShunt和XEN玻璃眼排水装置有效降低内脏压力和减少药物负担.
- 这两种设备都表现出良好的安全性.
- 在这个患者队列中,MicroShunt显示了与XEN相比更高的成功率的趋势.
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