结核病检测方面的进展
Jayson V Pagaduan1, Ghaith Altawallbeh1
1Intermountain Central Laboratory Intermountain Medical Center, Murray, UT, United States.
Advances in clinical chemistry
|September 6, 2023
概括
结核病 (TB) 仍然是全球主要的健康威胁,每年造成数百万人的死亡. 改善活跃和潜伏结核病的诊断工具对于实现终结结核病目标至关重要.
科学领域:
- 传染性疾病 传染性疾病
- 微生物学 微生物学
- 公共卫生 公共卫生
背景情况:
- 在全球范围内,结核病 (TB) 是单一传染病原体导致死亡的首要原因,直到COVID-19大流行.
- 2020年,有1000万人感染了结核病,150万人死亡.
- 大约有20亿人潜伏感染了Mycobacterium结核病 (MTB),有5-10%的终身风险发展为活跃的结核病.
研究的目的:
- 审查当前世界卫生组织 (WHO) 认可的结核病诊断测试.
- 讨论活跃和潜伏结核病的诊断和查测试方面的进展.
- 突出改善诊断对于实现2035年终结结核病目标的重要性.
主要方法:
- 审查当前的世界卫生组织认可的结核病诊断技术.
- 对结核病诊断的最新技术进步进行分析.
- 讨论潜伏结核病感染 (LTBI) 的查策略.
主要成果:
- 介绍了目前的诊断方法及其局限性.
- 探索用于更准确和更容易获得的结核病诊断的新兴技术.
- 强调了诊断和治疗潜伏性结核病的关键作用.
结论:
- 准确和易于使用的诊断工具对于结核病控制至关重要.
- 诊断技术的进步对于识别和治疗潜伏感染的个体至关重要.
- 实现终结结核病的目标需要对活跃结核病和潜伏结核病的诊断能力进行重大改进.
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