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相关概念视频

Nervous Tissue: Glial Cells01:31

Nervous Tissue: Glial Cells

3.1K
Glia, or neuroglia, are vital support cells that assist neurons in their functions. The term "glia" originates from the Greek word for "glue," reflecting their role in holding the nervous system together. These cells can be categorized into six types: four in the central nervous system (CNS) and two in the peripheral nervous system (PNS).
The CNS glial cell includes the astrocytes, the oligodendrocytes, the microglia, and the ependymal cells.
Astrocytes are star-shaped glial...
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Glial Cells01:04

Glial Cells

87.7K
Overview
87.7K
Phagocytosis00:41

Phagocytosis

6.4K
Cells pull particles inward and engulf them in spherical vesicles in an energy-requiring process called endocytosis. Phagocytosis ("cellular eating") is one of three major types of endocytosis. Cells use phagocytosis to take in large objects, such as other cells (or their debris), bacteria, and even viruses.
The objective of phagocytosis is often destruction. Cells use phagocytosis to eliminate unwelcome visitors, like pathogens (e.g., viruses and bacteria). Many immune system cells,...
6.4K
The Synapse02:47

The Synapse

125.5K
Neurons communicate with one another by passing on their electrical signals to other neurons. A synapse is the location where two neurons meet to exchange signals. At the synapse, the neuron that sends the signal is called the presynaptic cell, while the neuron that receives the message is called the postsynaptic cell. Note that most neurons can be both presynaptic and postsynaptic, as they both transmit and receive information.
125.5K
Delivery Pathways to the Lysosome01:36

Delivery Pathways to the Lysosome

6.6K
Eukaryotic cells use different mechanisms to eliminate toxic waste obsolete and worn-out substances. Lysosomes play a pivotal role in this, and hence, these substances are carried to the lysosome from other parts of the cell and extracellular space through different pathways. The most elaborately studied pathways to the lysosome are the endocytic pathways.
Endocytosis
In endocytosis, the cell membrane takes up macromolecules and particles from the surrounding medium. Clathrin-mediated...
6.6K
Synaptic Signaling01:09

Synaptic Signaling

5.6K
Neurons communicate at synapses, or junctions, to excite or inhibit the activity of other neurons or target cells, such as muscles. Synapses may be chemical or electrical.
Most synapses are chemical, meaning an electrical impulse or action potential spurs the release of chemical messengers called neurotransmitters. The neuron sending the signal is called the presynaptic neuron, and the neuron receiving the signal is the postsynaptic neuron.
The presynaptic neuron fires an action potential that...
5.6K

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相关实验视频

Updated: Jul 17, 2025

An Engulfment Assay: A Protocol to Assess Interactions Between CNS Phagocytes and Neurons
07:38

An Engulfment Assay: A Protocol to Assess Interactions Between CNS Phagocytes and Neurons

Published on: June 8, 2014

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[通过多种质细胞类型进行突触性细胞化]

Rena Kono1, Yuji Ikegaya1, Ryuta Koyama1

  • 1Laboratory of Chemical Pharmacology, Graduate School of Pharmaceutical Sciences, The University of Tokyo.

Nihon yakurigaku zasshi. Folia pharmacologica Japonica
|September 6, 2023
PubMed
概括
此摘要是机器生成的。

质细胞,包括微质细胞,星体细胞和寡体细胞,通过细胞分裂消除突触. 这篇评论探讨了多种质细胞类型如何协调神经元电路精炼的突触修剪.

科学领域:

  • 神经科学是一个神经科学.
  • 细胞生物学 细胞生物学

背景情况:

更多相关视频

A Novel In Vitro Live-imaging Assay of Astrocyte-mediated Phagocytosis Using pH Indicator-conjugated Synaptosomes
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A Novel In Vitro Live-imaging Assay of Astrocyte-mediated Phagocytosis Using pH Indicator-conjugated Synaptosomes

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In vitro Quantitative Imaging Assay for Phagocytosis of Dead Neuroblastoma Cells by iPSC-Macrophages
09:48

In vitro Quantitative Imaging Assay for Phagocytosis of Dead Neuroblastoma Cells by iPSC-Macrophages

Published on: February 14, 2021

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相关实验视频

Last Updated: Jul 17, 2025

An Engulfment Assay: A Protocol to Assess Interactions Between CNS Phagocytes and Neurons
07:38

An Engulfment Assay: A Protocol to Assess Interactions Between CNS Phagocytes and Neurons

Published on: June 8, 2014

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A Novel In Vitro Live-imaging Assay of Astrocyte-mediated Phagocytosis Using pH Indicator-conjugated Synaptosomes
06:43

A Novel In Vitro Live-imaging Assay of Astrocyte-mediated Phagocytosis Using pH Indicator-conjugated Synaptosomes

Published on: February 5, 2018

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In vitro Quantitative Imaging Assay for Phagocytosis of Dead Neuroblastoma Cells by iPSC-Macrophages
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In vitro Quantitative Imaging Assay for Phagocytosis of Dead Neuroblastoma Cells by iPSC-Macrophages

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  • 质细胞对于大脑发育和功能至关重要.
  • 突触连接形成神经元电路,质细胞调节它们的数量.
  • 突触性细胞分裂是质细胞削减突触的关键机制.

结论:

  • 多种质细胞类型通过 fagocytosis 促进突触修剪.
  • 了解突触调节中的质细胞相互作用对于理解神经元电路发育和可塑性至关重要.
  • 进一步研究质突触细胞形成的分子基础,可以揭示神经系统疾病的治疗点.