空气污染与心血管疾病首次入院和多次再入院的风险之间的关联
Shiyu Zhang1, Lan Chen1, Zhengmin Min Qian2
1Department of Epidemiology, School of Public Health, Sun Yat-Sen University, Guangzhou, Guangdong, China.
空气污染增加了心血管疾病 (CVD) 的入院和再入院风险. 现有心血管疾病的个体更容易受到环境空气污染物的影响,尤其是女性.
科学领域:
- 环境健康 环境健康
- 心血管医学 心血管医学
- 流行病学 流行病学
背景情况:
- 心血管疾病 (CVD) 构成了全球严重的健康负担.
- 环境空气污染对CVD吸收和再吸收的影响需要进一步调查.
研究的目的:
- 检查暴露于环境空气污染物和第一次因心血管疾病住院的风险之间的关联.
- 调查空气污染与心血管疾病多重再接收事件之间的联系.
- 评估是否具有先前存在的心血管疾病的个人更容易受到空气污染的影响.
主要方法:
- 利用了来自285,009名无心血管疾病参与者的英国生物库数据.
- 确定了四个主要的CVD入院事件:慢性缺血性心脏病 (CIHD),脑血管疾病,心房动和心力衰竭.
- 采用普伦蒂斯,威廉姆斯和彼得森-总时间模型来分析空气污染对首次入院和再入院的影响.
主要成果:
- 在12年的时间里,17,176名参与者因心血管疾病住院,其中6,203人重新入院.
- 在空气污染和首次CVD入院和再入院之间发现了显著的联系.
- 颗粒物 (≤2.5μm) 暴露与再入院的关联比第一次入院更强,特别是在脑血管疾病和CIHD方面.
- 与男性相比,女性的关联性更明显.
结论:
- 环境空气污染物涉及到心血管事件的初始和随后的入院.
- 以前患有心血管疾病的人似乎更容易受到空气污染的不利影响.
- 研究结果强调,需要制定公共卫生战略,以减轻空气污染对心血管健康的影响.
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