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2023年轴性脊椎关节炎的治疗概述

X Baraliakos¹, U Kiltz¹, I Kononenko¹

¹Ruhr Universität Bochum, and Rheumazentrum Ruhrgebiet, Herne, Germany.

Best practice & research. Clinical rheumatology

|September 6, 2023

概括

本综述总结了轴性脊髓关节炎 (axSpA) 治疗方法,包括体力活动,生活方式变化,NSAIDs和先进疗法,如生物和向合成修饰疾病的抗风湿药物 (bDMARD和tsDMARD). 它有助于优化患者护理.

科学领域:

类风湿病学类风湿病学
免疫学免疫学免疫学
物理医学和康复康复

背景情况:

轴性脊柱关节炎 (axSpA) 管理涉及各种治疗策略.
治疗决策受到疾病表现的影响,包括肌肉骨和肌肉骨外症状.

研究的目的:

审查 axSpA.目前的非药物和药物治疗选择.
为 axSpA.提供疾病修饰性抗风湿药物 (DMARDs) 的最新概述.
讨论通过患者子组选择,药物循环和逐渐缩小来优化治疗.

主要方法:

关于 axSpA 治疗的最新数据的文献综述.
综合有关身体活动,物理治疗和生活方式改变的信息.
非类固醇抗炎药物 (NSAIDs),bDMARDs和tsDMARDs的有效性和安全性的概述.

主要成果:

身体活动和物理治疗等非药物干预是axSpA管理的关键组成部分.
无 NSAID 药物仍然是基石,与日益增长的 bDMARD 和 tsDMARD 药物一起.
关于药物切换,逐渐减少和量身定制的治疗选择的数据对于改善结果至关重要.

结论:

优化axSpA治疗需要一个综合的方法,整合非药物和药物治疗方式.
随着bDMARDs和tsDMARDs的不断发展,提供了更多个性化的治疗选择.
基于证据的治疗选择和调整对于有效管理axSpA至关重要.

关键词:

轴性脊椎关节炎 (Axial spondyloarthritis) 是一个关节性关节炎.生物疾病修饰抗风湿药物生物疾病修饰抗风湿药物干联素-17 抑制剂干联素-17 抑制剂雅努斯酶抑制剂的使用治疗方法治疗方法瘤坏死因子抑制剂的使用

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