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一个超级增强剂调节的RNA结合蛋白级联驱动胰腺癌

Corina E Antal1,2,3, Tae Gyu Oh1,4, Stefan Aigner5

  • 1Gene Expression Laboratory, Salk Institute for Biological Studies, La Jolla, CA, 92037, USA.

Nature communications
|September 6, 2023
PubMed
概括

研究人员在胰腺癌 (PDAC) 中发现了一种可用药物的RNA结合蛋白级联,通过促进mRNA转化来增强瘤生长. 抑制这种途径对治疗PDAC显得有前途,特别是在Myc高的病例中.

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