主体和微生物组共同为环境适应做出贡献
Carola Petersen1, Inga K Hamerich1, Karen L Adair2
1Department of Evolutionary Ecology and Genetics, Kiel University, Kiel, Germany.
The ISME journal
|September 6, 2023
概括
与宿主相关的微生物或微生物组对于适应至关重要. 这项研究表明,宿主基因和微生物组合共同影响动物和微生物组合如何适应新环境.
科学领域:
- 微生物学 微生物学
- 进化生物学 进化生物学
- 基因组学就是基因组学.
背景情况:
- 微生物组,与宿主相关的微生物,对于基本功能至关重要.
- 主体微生物组组合 (元生物) 具有适应的潜力,可能比单独的宿主基因组更快.
- 宿主和微生物组对适应的共同贡献尚未完全理解.
研究的目的:
- 解开宿主和微生物组对超生物体在新环境中的适应性贡献.
- 为了研究微生物组组成和宿主遗传在适应过程中如何相互作用.
- 为联合宿主微生物群适应提供实验证据.
主要方法:
- 在实验室堆肥中,已经建立了与Caenorhabditis elegans和微生物的复制性mesocosms.
- 培养种群大约30个线虫代 (100天).
- 利用一个常见的花园实验来分析微生物组合,宿主遗传学和基因表达.
主要成果:
- 适应轨迹在中宇宙线上有所不同,有些适应性增加,有些适应性减少.
- 主体和微生物群之间的相互作用显著影响了对比的进化路径.
- 细菌/真菌组成和线虫基因表达的特定变化与健康状况的变化有关.
结论:
- 主体和微生物组共同影响适应新环境.
- 微生物组动力学和宿主遗传学相互作用,塑造了超生物体的进化.
- 这项研究提供了一个模型系统,用于剖析宿主微生物群的共同适应.
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