在大公河次区域 (Greater Mekong Subregion) 部署基于三重甲美西宁的组合疗法的战略
Freek de Haan1, Chanaki Amaratunga2,3, Van Anh Cao Thi4
1Copernicus Institute of Sustainable Development, Utrecht University, Utrecht, The Netherlands. F.dehaan@uu.nl.
Malaria journal
|September 6, 2023
概括
在大公河次区域,基于三次美素的组合疗法 (TACT) 面临着实施挑战. 诸如早期利益相关者参与和有针对性的信息传播等策略对于其未来的疟疾部署至关重要.
科学领域:
- 全球健康 全球健康
- 传染性疾病 传染性疾病
- 消除疟疾 消除疟疾
背景情况:
- 定性研究调查了基于三次美素的组合疗法 (TACT) 的实施挑战.
- 专注于东南亚大公河次区域 (GMS).
- 探索克服已识别的部署挑战的战略.
研究的目的:
- 确定在GMS中部署TACT的障碍.
- 探索克服这些障碍的有效策略.
- 为未来的疟疾控制和消除工作提供信息.
主要方法:
- 采用对39个主要利益相关者进行深入采访的定性研究.
- 在柬埔寨,越南和老人民共和国进行,这些国家面临着基于美素的组合疗法 (ACT) 失败.
- 包括在柬埔寨举行的参与性研讨会,讨论TACT部署场景.
主要成果:
- TACT被视为在GMS中消除Plasmodium falciparum疟疾的备用策略,特别是在抗素耐药性方面.
- 关键的挑战包括吸引决策者和医疗保健提供者,因为疟疾发病率低.
- 拟议的战略包括提前提交档案,利益相关者参与,并将TACT作为二线治疗,针对村庄疟疾工作人员进行信息传播.
结论:
- 在GMS中部署TACT面临着重大实施障碍.
- 为研究人员和政策制定者提出可行的策略,以应对挑战.
- 旨在支持未来的TACT部署,以打击耐药疟疾.
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