在中东的急性心力衰竭患者中开发和验证R-hf风险评分
Rajesh Rajan1, Mohammed Al Jarallah1, Ibrahim Al-Zakwani2,3
1Department of Cardiology, Sabah Al Ahmed Cardiac Centre, Kuwait City, Kuwait.
Oman medical journal
|September 7, 2023
概括
拉扬 (Rajan) 是一个名字.
科学领域:
- 心脏病学 心脏病学
- 腎臟病學 (nephrology) 是一種醫學.
- 生物标志物 生物标志物
背景情况:
- 拉扬心力衰竭 (R-hf) 风险评分是为心力衰竭患者的风险分层而开发的.
- 急性不补偿性心力衰竭 (ADHF) 需要准确的预后工具来管理患者.
研究的目的:
- 为了验证R-hf风险评分的预后能力在急性不补偿心力衰竭患者的跨国队列中.
- 评估R-hf风险评分与3个月和12个月的所有原因死亡率之间的关联.
主要方法:
- 来自七个中东国家的776名心力衰竭患者的前性,跨国,多中心注册.
- 使用估计的淋巴细胞过率,左心室喷射分数,血红蛋白和N终端前脑尿性来计算R-hf风险得分.
- 进行了单变量和多变量逻辑回归分析,以评估得分的预测准确性.
主要成果:
- 较低R-hf风险分数 (≤5) 的患者显示出更高的3个月全因死亡率趋势 (aOR=4.28,p=0.067).
- 在较低R-hf风险得分组 (aOR=3.84,p=0.021) 与最高得分组 (≥50) 相比,在12个月内所有原因死亡率显著增加.
- 该研究包括776名患者,平均年龄为62.0±14.0岁,62.4%是男性.
结论:
- 较低的R-hf风险得分与出院后3个月和12个月所有原因累积死亡的风险增加有关.
- R-hf风险评分在急性不补偿性心力衰竭的风险分层患者中显示出潜在的实用性.
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