一个概念框架来表征多种长期疾病的生命过程决定因素多重疾病多重疾病
Sebastian Stannard1, Ann Berrington2, Shantini Paranjothy3
1School of Primary Care, Population Sciences and Medical Education, Faculty of Medicine, Southampton General Hospital, Southampton, UK.
Journal of multimorbidity and comorbidity
|September 7, 2023
概括
生命早期的因素会影响长期的多病症风险. 一个与公众共同制作的新框架确定了未来研究和预防策略的关键领域,如不利的童年经历和社会经济因素.
科学领域:
- 公共卫生 公共卫生
- 流行病学 流行病学
- 生命历程 研究 研究 研究
背景情况:
- 早期的生活经历 (怀孕前到18岁) 显著影响发展多种长期疾病的风险 (多重疾病).
- 对这些早期决定因素及其相互关系的全面理解对于有效的多病症研究和预防至关重要.
- 现有的研究和政策往往忽视了公众参与所突显的关键因素.
研究的目的:
- 开发一个概念框架,以对人口层面的早期生命决定未来多病症的决定因素进行表征.
- 为未来的多病症病因学和预防研究提供概念框架.
- 将公众的观点纳入了解生命早期对长期健康的影响.
主要方法:
- 这项研究是多学科生态系统的一部分,旨在研究生命过程决定因素和预防早期发病的繁重多病症 (MELD-B) 倡议.
- 对现有研究证据和政策的审查为决定性领域的概念化提供了信息.
- 通过两次研讨会与公众参与共同制作塑造了框架.
主要成果:
- 确定了一些关键的早期生命风险因素领域,包括不良的童年经历,社会经济地位,社会和物理环境以及教育.
- 政策建议主要关注个人层面的因素,与研究中强调的更广泛的决定因素形成鲜明对比.
- 公共贡献者强调宗教,精神,健康查和饮食等领域,这些领域在现有证据和政策中代表性不足.
结论:
- 共同制作的概念框架可以指导未来的研究,使用各种数据源来识别面临风险的人群.
- 该框架支持制定有针对性的公共卫生政策,以预防早期多种疾病.
- 整合公众的见解丰富了对早期生命决定因素的理解,以进行有效的健康干预.
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