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Updated: Jul 17, 2025

Repressing Gene Transcription by Redirecting Cellular Machinery with Chemical Epigenetic Modifiers
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洞察HDAC3和NCoR1/NCoR2联合抑制体复合物的功能在代谢疾病中的作用

Harikrishnareddy Paluvai1,2, Kumar D Shanmukha1,2, Jens Tyedmers1,2

  • 1Institute of Experimental Cardiology, Heidelberg University, Heidelberg, Germany.

Frontiers in molecular biosciences
|September 7, 2023
PubMed
概括

基因组脱乙酶3 (HDAC3) 和核受体共抑制剂 (NCoR1/2) 调节新陈代谢. 它们的相互作用影响心脏代谢疾病,表明治疗潜力.

关键词:
这是GPS2GPS2.在 HDAC3 中,HDAC3 是没有NCoR1的情况.这些是PPARs.这就是 SMRT 的意思.

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