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相关概念视频

First Pass Effect01:12

First Pass Effect

5.6K
Presystemic elimination, or the first-pass effect, is the metabolism of drugs that reduces their effective concentration at the site of action. Apart from the first-pass effect, the systemic bioavailability of the drug is also reduced by other factors, including incomplete absorption or chemical degradation of drugs.
Depending on the route of administration, drugs can be metabolized in the liver, intestine, lungs, and vasculature. Orally administered drugs are first absorbed through the...
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Factors Influencing Drug Absorption: Presystemic Elimination01:24

Factors Influencing Drug Absorption: Presystemic Elimination

260
The pharmacokinetic journey of oral drugs begins with a crucial first pass through the hepatic portal system, called the first-pass effect. This first pass significantly impacts bioavailability — the proportion of a drug that enters systemic circulation and is available for therapeutic action. The primary route sees the drug absorbed by intestinal membranes and then shunted to the liver via the hepatic portal vein. Here, pre-systemic elimination occurs as drugs face metabolism or biliary...
260
Reliability and Validity01:29

Reliability and Validity

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Reliability and validity are two important considerations that must be made with any type of data collection. Reliability refers to the ability to consistently produce a given result. In the context of psychological research, this would mean that any instruments or tools used to collect data do so in consistent, reproducible ways.
12.8K
Preclinical Development: Overview01:28

Preclinical Development: Overview

4.5K
Preclinical development consists of a series of tests that ensure the safety and efficacy of a new therapeutic compound before it is tested in humans. There are four main phases to this process. First, safety pharmacology tests are conducted to ensure the drug does not produce any acutely harmful effects. These tests examine parameters such as bronchoconstriction, cardiac dysrhythmias, blood pressure changes, and ataxia. Next, preliminary toxicological testing is performed to determine the...
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Factors Influencing Bioavailability: First-Pass Elimination01:23

Factors Influencing Bioavailability: First-Pass Elimination

6.5K
When a drug is taken orally, it undergoes a journey starting from the gastrointestinal (GI) tract, passing through the portal vein, reaching the liver, and finally entering the systemic circulation. This process involves the absorption of the drug across the GI tract. The liver is the primary site for metabolizing the drug, with some metabolism also occurring in the gut wall. This journey significantly reduces the quantity of the drug that reaches the systemic circulation, a phenomenon known as...
6.5K
Nursing Clinical Information System01:27

Nursing Clinical Information System

812
Nursing Clinical Information System (NCIS)
A Nursing Clinical Information System (NCIS) is a specialized type of healthcare information system tailored to meet the unique needs of nursing practice. It incorporates the principles of nursing informatics to streamline information management and improve the quality of care delivery.
Critical attributes of NCIS include:
812

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E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy
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E-Patient Counseling Trial E-PACO: Computer Based Education versus Nurse Counseling for Patients to Prepare for Colonoscopy

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商业NCLEX-RN准备产品对首次通过率的影响

Lisa Scandale Lewis1, Tonya Willingham2, John Myers1

  • 1Duke University School of Nursing, Durham, NC, USA.

SAGE open nursing
|September 7, 2023
PubMed
概括

商业测试准备产品并没有显著影响国家委员会执照考试注册护士 (NCLEX-RN) 首次通过率. 为准备NCLEX-RN的护理学生推指导导使用和个性化计划.

科学领域:

  • 护理教育 护理教育
  • 卫生专业 许可证 许可证 医疗专业

背景情况:

  • 国家委员会执照考试注册护士 (NCLEX-RN) 对于进入护士职业至关重要.
  • 首次通过率是护理课程和学生的关键结果指标.

研究的目的:

  • 调查商业NCLEX-RN测试准备产品对首次通过率的影响.
  • 为了比较使用商业产品和对照组的学生之间的人口统计数据和通过率.

主要方法:

  • 数据来自6个机构的688名首次参加NCLEX-RN的受试者.
  • 干预组 (n=396) 获得了一个商业测试准备产品的6个月订阅.
  • 对照组 (n=292) 没有使用该产品.

主要成果:

  • 干预组中25岁以下的学生比例较高 (55.8%对34.6%,p < .001).
  • 干预组和对照组之间没有观察到NCLEX-RN通过率的显著差异.
  • 除了年龄之外,人口统计数据在各组之间没有显著差异.

结论:

  • 商用NCLEX-RN测试准备产品并没有对首次通过率产生重大影响.
  • 建议指导教师使用测试准备工具和个性化学生支持计划.
关键词:
在NCLEX-RN中,你必须通过NCLEX.护理教育 护理教育学生的成功 学生的成功

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  • 强调需要全面的战略,以支持护理学生的NCLEX-RN成功.