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Updated: Aug 7, 2026

Systems Biology of Metabolic Regulation by Estrogen Receptor Signaling in Breast Cancer
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液体活检对激素敏感乳腺癌ESR1突变分析的验证:一个聚合的元分析

Omar Najim1,2, Konstantinos Papadimitriou1,2,3, Glenn Broeckx1,2,4

  • 1Multidisciplinary Breast Clinic Antwerp University Hospital, University of Antwerp, Edegem, Belgium.

Frontiers in oncology
|September 7, 2023
PubMed
概括

液体活检有效检测雌激素受体1 (ESR1) 突变,为组织活检提供一种非侵入性的替代方案. 该方法有助于监测治疗敏感性,并指导患者的治疗策略.

关键词:
在ESR1中使用ESR1.数字PCR是数字的PCR.液体活检活检液体活检已经转移的乳腺癌.这是下一代测序.

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相关概念视频

Enzyme-Linked Immunosorbent Assay01:33

Enzyme-Linked Immunosorbent Assay

In 1971, Peter Perlman and Eva Engvall developed an Enzyme-linked immunosorbent assay (ELISA or EIA). ELISA differs from western blot in that the assays are conducted in microtiter plates or in vivo rather than on an absorbent membrane.
There are many different types of ELISAs, but they all involve an antibody molecule whose constant region binds an enzyme, leaving the variable region free to bind its specific antigen.  Enzyme-substrate reaction allows the antigen to be visualized or quantified.