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Updated: Jul 17, 2025

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剖析METTL3对前列腺癌替代拼接的影响

Lin Wang1,2, Ling Shi2, Yonghao Liang2

  • 1Metabolic Disease Research Center, Zhengzhou Central Hospital Affiliated to Zhengzhou University, Zhengzhou, China.

Frontiers in oncology
|September 7, 2023
PubMed
概括

在前列腺癌 (PCa) 中,METTL3通过影响外子跳转和内子保留来调节替代拼接 (AS). 由N6-甲基氨酸 (m6A) 影响的METTL3-依赖性AS事件突出显示MKNK2AS事件作为潜在的PCa生物标志物.

关键词:
在METTL3中,METTL3是METTL3的第一个类型.在MKNK2MKNK2中.N 6 - - 甲基氨酸通过RNA拼接进行RNA拼接.纳米孔直接RNA测序前列腺癌是前列腺癌.

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